References
A decade of HPAE gene delivery research.
Selected publications supporting highly branched poly(β-amino ester) gene delivery, non-viral delivery, CRISPR delivery, skin/lung gene therapy and biomedical polymer applications.
2025
1 publicationGuanidyl-rich highly branched poly(β-amino ester)s for delivery of dual CRISPR ribonucleoprotein for large DNA fragment deletion
2024
4 publicationsHighly branched poly β-amino ester / CpG-depleted CFTR plasmid nanoparticles for non-viral gene therapy in lung cystic fibrosis
Nonviral CRISPR/Cas9 mutagenesis for streamlined generation of mouse lung cancer models
Cyclization-Enhanced Poly(β-Amino Ester)s Vectors for Efficient CRISPR Gene Editing Therapy
Backbone Cationized Highly Branched Poly(β-Amino Ester)s as Enhanced Delivery Vectors in Non-Viral Gene Therapy
2023
7 publicationsCRISPR/Cas9 Non-viral Gene Editing Therapy for Topical Treatment of Recessive Dystrophic Epidermolysis Bullosa
Guanidyl-Rich Poly(Amino Ester)s for Universal Cytosolic Protein Delivery and CRISPR Cas9 RNP-Based Gene Editing
Enhanced gene transfection efficacy and safety through granular hydrogel mediated gene delivery process
3D Macrocyclic Structure Boosted Gene Delivery: Multi-cyclic Poly(β-Amino Ester)s from Step Growth Polymerization
Branch Unit Distribution Matters for Gene Delivery
A New Optimization Strategy of Highly Branched Poly(β-Amino Ester) for Enhanced Gene Delivery
Highly branched poly(β-amino ester)s with narrow molecular weight distribution: fractionation and gene transfection activity
2021
2 publicationsHighly Branched Poly(β-amino ester)s for Gene Delivery in Hereditary Skin Diseases
Non-viral delivery of CRISPR–Cas9 complexes for targeted gene editing via a polymer delivery system
2020
1 publicationEffects of Branching Strategy on the Gene Transfection of Highly Branched Poly(β-amino ester)s
2019
2 publicationsEfficient and Robust Highly Branched Poly(β-Amino Ester) Minicircle COL7A1 Nanoparticles for RDEB Keratinocytes
Highly branched poly(β-amino ester) delivery of minicircle DNA for neurodegenerative disease cells
2018
1 publicationMultifunctional Linear-Branched Hybrid Poly(β-Amino Ester) via Oligomer Combination Approach
2017
4 publicationsBrushlike Cationic Polymers with Low Charge Density for Gene Delivery
Star poly(β-amino esters) from the Combination of Linear PBAE and Polyethyleneimine
Highly Branched poly(5-amino-1-pentanol-co-1,4-butanediol diacrylate) for High Performance Gene Transfection
Thermo- and pH-Responsive Coacervate-Forming Hyperbranched Poly(β-amino ester)s for Selective Cell Binding
2016
5 publicationsHighly Branched Poly(β-amino ester)s for Skin Gene Therapy
Biodegradable Highly Branched Poly(β-amino ester)s for Targeted Cancer Cell Gene Transfection
A non-viral gene therapy for treatment of recessive dystrophic epidermolysis bullosa
Highly Branched Poly(β-amino esters) for Non-Viral Gene Delivery: high transfection efficiency and low toxicity
The Transition from Linear to Highly Branched Poly(β-amino ester)s: Branching Matters
2015
1 publicationTailoring highly branched poly(β-amino ester)s: a synthetic platform for epidermal gene therapy
